Вирус гриппа может провоцировать аутоиммунные заболевания

Вирус гриппа может провоцировать аутоиммунные заболевания


Объяснен механизм развития иммунитета против собственных белков организма в результате вирусной инфекции.


Вирус гриппа может провоцировать аутоиммунные заболевания

Обнаружен важный врожденный механизм иммунной защиты против грибковых инфекций

Аутоиммунные заболевания связаны с ошибочной реакцией иммунитета, которая приводит к активации иммунных клеток против белков самого организма. Специалистам известно, что такие заболевания могут вызываться вирусной инфекцией, однако, это механизм не был прояснен. Группа ученых из Базеля Швейцария совместно с коллегами из США предложила объяснение этого феномена.


Иммунные клетки распознают белки на поверхности близлежащих клеток и воспринимают их с клеточной мембраны. В некоторых случаях в этом процессе случаются ошибки. Т-лимфоцит может одновременно воспринимать белки вируса например, грипп в совокупности с белками близлежащих клеточных мембран. В этом случае возникает иммунная реакция не только на белки вируса, но и на собственные белки организма. Исследователи обнаружили этот механизм в отношении аутоиммунного воспаления мозга у лабораторных мышей в связи с инфекцией вируса гриппа.

Источник: medikforum.ru
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